Frontiers in Neuroendocrinology Estrogen receptor beta messenger ribonucleic acid expression within the human forebrain: Distinct distribution pattern to ER alpha mRNA. Sexual behavior: The product of perinatal hormonal and prepubertal social factors.
How to cite this article. Philadelphia: WB Saunders. Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Gender differences in rat neuropathic pain sensitivity is dependent on strain.
The fact that defeminisation is a distinct and active process negates the notion that the female brain is an undifferentiated brain. Acta Obstet Gynecol Scand. Developmental Psychobiology 40 : — Deleterious effects of dihydrotestosterone on cerebral ischemic injury. Here, we will review both clinical and laboratory-based research evidence revealing important sex-related differences in cannabinoid effects, and put forward some suggestions for future studies to fill the gap in our knowledge of gender-specific bias in cannabinoid pharmacology.
GABA receptors make teens resistant to input. Sex-dependent differences have been frequently observed in the biological and behavioural effects of substances of abuse, including cannabis. As a consequence of the action of sex steroid hormones, important modifications take place in the CNS during the embryonic stage, also observed in puberty and adolescence Schulz et al.
Myelin confers on axons their characteristic white appearance, and thus myelination is responsible for the increase in white matter in the brain during adolescence Morriss et al.
A cohort of age and weight matched WTM with Sry endogenously present on the Y chromosome was used to compare the effects of Sry transgene with endogenous Sry. Developmental Psychobiology 40 : — Its inhibitory capacity is explained by GABA which, when faced by an excitatory input, generates an anion chloride influx through the GABA A receptor, triggering neuron hyper polarizations, which prevents action potentials from unleashing and, therefore, the stimuli from propagating as nerve impulses.
Intact female rats are more susceptible to the development of tactile allodynia than ovariectomized female rats following partial sciatic nerve ligation PSNL Neurosci Lett.
Female rats are more susceptible to the development of neuropathic pain using the partial sciatic nerve ligation PSNL model. Similarly, the severity of experimental arthritis has been shown to be greater in gonadally intact female rats than in male rats Green, Vaginal opening and vaginal epithelium following ovariectomy in newborn rats.
Services on Demand Journal. Effect of estrogen withdrawal on nitric oxide synthase expression and apoptosis in the rat vagina. Lumbar radiculopathy Lumbar radiculopathy LR was surgically induced using the procedure of Hashizume et al.