Our samples from cancer patients were all taken after diagnosis, so there is a possibility that treatment may have affected the degree of aneuploidy, i. Our data showed a larger proportion of cells with sex chromosome aneuploidy especially among the oldest group. Figure 1.
Ali et al. In summary, we have found that sex chromosome aneuploidy is common in uncultured white blood cells from normal men and those with breast cancer, and increases greatly with age. About this book Introduction Wild crop relatives are now playing a significant part in the elucidation and improvement of the genomes of their cultivated counterparts.
Linking functional decline of telomeres, mitochondria and stem cells during ageing. In it was shown that human chromosome counts, obtained by examining peripheral blood stimulated to divide in culture by phytohaemagglutin, showed an ageing effect that was present both in individuals with a normal chromosome constitution and in individuals with Down and Klinefelter Syndromes Jacobs et al Our data showed a larger proportion of cells with sex chromosome aneuploidy especially among the oldest group.
Download references. Author information Article notes Copyright and License information Disclaimer. In virtually all studies aneuploidy of the X chromosomes in females was very much more frequent than that of the Y chromosome age related sex chromosome aneuploidy addition in Nambour males.
Correspondence to A J Swerdlow. The enzyme that maintains the telomere is called telomerase. International Journal of Molecular Biology In male human spermatogenesisproducing of four haploid cells 23 chromosomes, 1N from the two haploid cells 23 chromosomes, 1Neach of the chromosomes consisting of two sister chromatids produced in meiosis I.
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Notes The authors declare no conflict of interest. About this book Introduction Wild crop relatives are now playing a significant part in the elucidation and improvement of the genomes of their cultivated counterparts. From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.
It contains chapters written by nearly well-known authors from about 40 countries.